The running attack has been slowed of late. Buffalo finished with a season-low 68 yards rushing against the Jets. That marked the fourth time in five games the Bills haven't broken 100 yards.
Spiller said the run game needs to be fixed, before adding that his first priority is taking time off.
"We've been going at it for a long time, so it's going to be good for some guys to get away and refresh," Spiller said. "The last thing you want to do is fry your brain."